> Biopsies test only small areas of the prostate, so they can miss more advanced or aggressive cancer cells, providing an incomplete picture.
Not an MD - but wasn't this well known decades ago? If you take a modest number of small samples from a (relatively) large, heterogeneous organ - it's old-fashioned statistics as to how representative your sample set will (or won't) be.
> Biopsies test only small areas of the prostate, so they can miss more advanced or aggressive cancer cells, providing an incomplete picture.
Not an MD - but wasn't this well known decades ago? If you take a modest number of small samples from a (relatively) large, heterogeneous organ - it's old-fashioned statistics as to how representative your sample set will (or won't) be.